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Article

Asperger syndrome and early-onset schizophrenia associated with a novel MECP2 deleterious missense variant.

Psychiatric genetics - 1 Jun 2017

Curie Aurore, Lesca Gaëtan, Bussy Gérald, Manificat Sabine, Arnaud Valérie, Gonzalez Sibylle, Revol Olivier, Calender Alain, Gérard Daniel, des Portes Vincent

Abstract excerpt

Methyl-CpG-binding protein 2 (MECP2) deleterious variants, which are responsible for Rett syndrome in girls, are involved in a wide spectrum of developmental disabilities in males. A neuropsychiatric phenotype without intellectual disability is uncommon in patients with MECP2 deleterious variants. We report on two dizygotic twins with an MECP2-related psychiatric disorder without intellectual disability....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28230711
DOI: 10.1097/YPG.0000000000000165

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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