Article
Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola.
Scientific reports - 23 Feb 2017
Perdigão João, Clemente Sofia, Ramos Jorge, Masakidi Pedro, Machado Diana, Silva Carla, Couto Isabel, Viveiros Miguel, Taveira Nuno, Portugal Isabel
Abstract excerpt
Tuberculosis (TB) poses a serious public health problem in Angola. No surveillance data on drug resistance is available and nothing is known regarding the genetic diversity and population structure of circulating Mycobacterium tuberculosis strains. Here, we have genotyped and evaluated drug susceptibility of 89 Mycobacterium tuberculosis clinical isolates from Luanda. Thirty-three different spoligotype profiles...
Topics
- Angola
- Anti-Bacterial Agents
- Antitubercular Agents
- DNA, Bacterial
- Drug Resistance, Multiple, Bacterial
- Evolution, Molecular
- Female
- Genetic Variation
- Genotyping Techniques
- Humans