Article
CD14+CD16++ "nonclassical" monocytes are associated with endothelial dysfunction in patients with coronary artery disease.
Thrombosis and haemostasis - 3 May 2017
Urbanski Karol, Ludew Dominik, Filip Grzegorz, Filip Magdalena, Sagan Agnieszka, Szczepaniak Piotr, Grudzien Grzegorz, Sadowski Jerzy, Jasiewicz-Honkisz Barbara, Sliwa Tomasz, Kapelak Boguslaw, McGinnigle Eilidh, Mikolajczyk Tomasz, Guzik Tomasz J
Abstract excerpt
Endothelial dysfunction and inflammation are key mechanisms of vascular disease. We hypothesised that heterogeneity of monocyte subpopulations may be related to the development of vascular dysfunction in coronary artery disease (CAD). Therefore, we examined the relationships between monocyte subsets (CD14++CD16- "classical - Mon1", CD14++CD16+ "intermediate - Mon2" and CD14+CD16++ "nonclassical - Mon3"),...
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