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Article

Requirement of the CroRS Two-Component System for Resistance to Cell Wall-Targeting Antimicrobials in Enterococcus faecium

21 Feb 2017

Abstract excerpt

ABSTRACT Enterococci are serious opportunistic pathogens that are resistant to many cell wall-targeting antibiotics. The CroRS two-component signaling system responds to antibiotic-mediated cell wall stress and is critical for resistance to cell wall-targeting antibiotics in Enterococcus faecalis . Here, we identify and characterize an orthologous two-component system found in Enterococcus faecium that is...

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PMID: 28223383
DOI: 10.1128/aac.02461-16

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