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Article

CD4+ CD25+ GARP+ regulatory T cells display a compromised suppressive function in patients with dilated cardiomyopathy.

Immunology - 1 Jul 2017

Wei Yuzhen, Yu Kunwu, Wei Hui, Su Xin, Zhu Ruirui, Shi Huairui, Sun Haitao, Luo Quan, Xu Wenbin, Xiao Junhui, Zhong Yucheng, Zeng Qiutang

Abstract excerpt

Dilated cardiomyopathy (DCM) is a lethal inflammatory heart disease and closely connected with dysfunction of the immune system. Glycoprotein A repetitions predominant (GARP) expressed on activated CD4+ T cells with suppressive activity has been established. This study aimed to investigate the frequency and function of circulating CD4+ CD25+ GARP+ regulatory T (Treg) cells in DCM. Forty-five DCM patients and 46...

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Identifiers

PMID: 28207945
DOI: 10.1111/imm.12728
PMCID: PMC5461097

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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