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Article

Rdh10 loss-of-function and perturbed retinoid signaling underlies the etiology of choanal atresia.

Human molecular genetics - 1 Apr 2017

Kurosaka Hiroshi, Wang Qi, Sandell Lisa, Yamashiro Takashi, Trainor Paul A

Abstract excerpt

Craniofacial development is a complex process that involves sequential growth and fusion of the facial prominences. When these processes fail, congenital craniofacial anomalies can occur. For example, choanal atresia (CA) is a congenital craniofacial anomaly in which the connection between the nasal airway and nasopharynx is completely blocked. CA occurs in approximately 1/5000 live births and is a frequent...

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Source

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Identifiers

PMID: 28169399
DOI: 10.1093/hmg/ddx031
PMCID: PMC5390677

Genes

RDH10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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