Article
Predictors of treatment efficacy and ALT non-normalization with sofosbuvir/ribavirin therapy for patients with hepatitis C virus genotype 2.
Journal of medical virology - 1 Sept 2017
Watanabe Takao, Tokumoto Yoshio, Joko Kouji, Michitaka Kojiro, Horiike Norio, Tanaka Yoshinori, Tada Fujimasa, Kisaka Yoshiyasu, Nakanishi Seiji, Nonaka Takashi, Yamauchi Kazuhiko, Hirooka Masashi, Abe Masanori, Hiasa Yoichi
Abstract excerpt
The tolerability and efficacy of sofosbuvir and ribavirin in patients infected with hepatitis C virus (HCV) genotype 2 were investigated under actual clinical conditions. A total of 208 patients with chronic HCV genotype 2 infection were treated with sofosbuvir 400 mg and ribavirin (weight-based dosing) for 12 weeks. Treatment discontinuation and sustained virological response 12 (SVR12) were evaluated. Moreover,...
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