Article
PVX-tolerant potato development using a nucleic acid-hydrolyzing recombinant antibody.
Acta virologica - 1 Jan 2000
Yang J-G, Hwang K-H, Kil E-J, Park J, Cho S, Lee Y-G, Auh C-K, Rhee Y, Lee S
Abstract excerpt
3D8 scFv, a catalytic recombinant antibody developed in the MRL mouse, exhibits nucleic acid-hydrolyzing activity. Previous studies have demonstrated that tobacco plants harboring 3D8 scFv antibodies showed broad-spectrum resistance to infection by both DNA and RNA viruses. In this study, potatoes were transformed with the 3D8 scFv gene and screened by potato virus X (PVX) challenge. Starting with the T0 and T1...
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