Pore-Forming Proteins as Mediators of Novel Epigenetic Mechanism of Epilepsy

Abstract excerpt

Epilepsy is a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. In the last two decades, numerous gene defects underlying different forms of epilepsy have been identified with most of these genes encoding ion channel proteins. Despite these developments, the etiology of majority of non-familial epilepsies have no known associated genetic mutations and cannot be...

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