Article
Dysarthria and broader motor speech deficits in Dravet syndrome.
Neurology - 21 Feb 2017
Turner Samantha J, Brown Amy, Arpone Marta, Anderson Vicki, Morgan Angela T, Scheffer Ingrid E
Abstract excerpt
OBJECTIVE: To analyze the oral motor, speech, and language phenotype in 20 children and adults with Dravet syndrome (DS) associated with mutations in SCN1A. METHODS: Fifteen verbal and 5 minimally verbal DS patients with SCN1A mutations (aged 15 months-28 years) underwent a tailored assessment battery. RESULTS: Speech was characterized by imprecise articulation, abnormal nasal resonance, voice, and pitch, and...
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