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Article

Antibody gene transfer with adeno‐associated viral vectors as a method for HIV prevention

1 Jan 2017

Abstract excerpt

Broadly neutralizing antibodies (bNAbs) against human immunodeficiency virus (HIV) show great promise in HIV prevention as they are capable of potently neutralizing a considerable breadth of genetically diverse strains. Passive transfer of monoclonal bNAb proteins can confer protection in animal models of HIV infection at modest concentrations, inspiring efforts to develop an HIV vaccine capable of eliciting bNAb...

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PMID: 28133808
DOI: 10.1111/imr.12478

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