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Article

Polymorphisms in genes involved in enamel development are associated with dental fluorosis.

Archives of oral biology - 1 Apr 2017

Küchler Erika Calvano, Tannure Patricia Nivoloni, Oliveira Daniela Silva Barroso de, Charone Senda, Nelson-Filho Paulo, Silva Raquel Assed Bezerra da, Costa Marcelo de Castro, Antunes Leonardo Santos, Calasans Maia Mônica Diuana, Antunes Lívia Azeredo Alves

Abstract excerpt

OBJECTIVE: To evaluate the association between polymorphisms in DLX1, DLX2, MMP13, TIMP1 and TIMP2 genes with dental fluorosis (DF) phenotype. DESIGN: Four hundred and eighty one subjects (108 with DF and 373 DF free) from 6 to 18 years of age were recruited. This population lived in Rio de Janeiro, a city with fluoridation of public water supplies. DF was assessed using the Deańs index modified. Only erupted...

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Identifiers

PMID: 28131910
DOI: 10.1016/j.archoralbio.2017.01.009

Genes

DLX1
DLX2
TIMP1
MMP13
TIMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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