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Article

Fine mapping genetic associations between the HLA region and extremely high intelligence.

Scientific reports - 24 Jan 2017

Zabaneh Delilah, Krapohl Eva, Simpson Michael A, Miller Mike B, Iacono William G, McGue Matt, Putallaz Martha, Lubinski David, Plomin Robert, Breen Gerome

Abstract excerpt

General cognitive ability (intelligence) is one of the most heritable behavioural traits and most predictive of socially important outcomes and health. We hypothesized that some of the missing heritability of IQ might lie hidden in the human leukocyte antigen (HLA) region, which plays a critical role in many diseases and traits but is not well tagged in conventional GWAS. Using a uniquely powered design, we...

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Identifiers

PMID: 28117369
DOI: 10.1038/srep41182
PMCID: PMC5259706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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