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Article

Combinatorics of Tandem Duplication Random Loss Mutations on Circular Genomes.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Hartmann Tom, Chu An-Chiang, Middendorf Martin, Bernt Matthias

Abstract excerpt

The tandem duplication random loss operation (TDRL) is an important genome rearrangement operation in metazoan mitochondrial genomes. A TDRL consists of a duplication of a contiguous set of genes in tandem followed by a random loss of one copy of each duplicated gene. This paper presents an analysis of the combinatorics of TDRLs on circular genomes, e.g., the mitochondrial genome. In particular, results on TDRLs...

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Identifiers

PMID: 28114075
DOI: 10.1109/TCBB.2016.2613522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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