Article
Amphimeric mitochondrial genomes of petite mutants of yeast. III. Generation by linking two secondary-structure-dependent illegitimate recombination events.
Current genetics - 1 Feb 1999
Rayko E, Goursot R
Abstract excerpt
The generation of amphimeric mitochondrial petite genomes of yeast can be explained by a process that links together two illegitimate recombination events, each involving a pair of short inverted repeats. Following "diagonal" double-strand breaks and inter-strand ligations at both possible stem-and-loop structures, a subgenomic single-stranded DNA circle can be excised. This circle comprises four building blocks...
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