Article
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.
Cell stem cell - 2 Mar 2017
Guimarães-Camboa Nuno, Cattaneo Paola, Sun Yunfu, Moore-Morris Thomas, Gu Yusu, Dalton Nancy D, Rockenstein Edward, Masliah Eliezer, Peterson Kirk L, Stallcup William B, Chen Ju, Evans Sylvia M
Abstract excerpt
Pericytes are widely believed to function as mesenchymal stem cells (MSCs), multipotent tissue-resident progenitors with great potential for regenerative medicine. Cultured pericytes isolated from distinct tissues can differentiate into multiple cell types in vitro or following transplantation in vivo. However, the cell fate plasticity of endogenous pericytes in vivo remains unclear. Here, we show that the...
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