Article
Associations between hepatic miRNA expression, liver triacylglycerols and gut microbiota during metabolic adaptation to high-fat diet in mice.
Diabetologia - 1 Apr 2017
Blasco-Baque Vincent, Coupé Berengère, Fabre Aurelie, Handgraaf Sandra, Gourdy Pierre, Arnal Jean-François, Courtney Michael, Schuster-Klein Carole, Guardiola Beatrice, Tercé François, Burcelin Rémy, Serino Matteo
Abstract excerpt
AIMS/HYPOTHESIS: Despite the current pandemic of metabolic diseases, our understanding of the diverse nature of the development of metabolic alterations in people who eat a high-fat diet (HFD) is still poor. We recently demonstrated a cardio-metabolic adaptation in mice fed an HFD, which was characterised by a specific gut and periodontal microbiota profile. Since the severity of hepatic disease is characterised...
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