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Article

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota.

Gut - 1 Apr 2012

Serino Matteo, Luche Elodie, Gres Sandra, Baylac Audrey, Bergé Mathieu, Cenac Claire, Waget Aurelie, Klopp Pascale, Iacovoni Jason, Klopp Christophe, Mariette Jerome, Bouchez Olivier, Lluch Jerome, Ouarné Francoise, Monsan Pierre, Valet Philippe, Roques Christine, Amar Jacques, Bouloumié Anne, Théodorou Vassilia, Burcelin Remy

Abstract excerpt

OBJECTIVE: The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside from changes in genetic background and diet, could sign different metabolic phenotypes in mice. METHODS: The unique animal model of metabolic adaptation was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22110050
DOI: 10.1136/gutjnl-2011-301012
PMCID: PMC3292714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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