Article
Polymorphisms and Mutational Covariation Associated with Death in a Prospective Cohort of HIV/AIDS Patients Receiving Long-Term ART in China.
PloS one - 1 Jan 2017
Liu Pengtao, Feng Yi, Wu Jianjun, Tian Suian, Su Bin, Wang Zhe, Liao Lingjie, Xing Hui, You Yinghui, Shao Yiming, Ruan Yuhua
Abstract excerpt
BACKGROUND: HIV drug resistance is associated with faster clinical progression of AIDS. However, the effect of significant polymorphisms and mutational covariation on mortality among HIV/AIDS patients receiving long-term antiretroviral therapy (ART), have rarely been studied. METHODS: In this prospective cohort study from December 2003 to December 2014, we present a new computational modelling approach based on...
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