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Article

Sex determination and maintenance: the role of DMRT1 and FOXL2

18 Nov 2016

Abstract excerpt

In many species, including mammals, sex determination is genetically based. The sex chromosomes that individuals carry determine sex identity. Although the genetic base of phenotypic sex is determined at the moment of fertilization, the development of testes or ovaries in the bipotential early gonads takes place during embryogenesis. During development, sex determination depends upon very few critical genes. When...

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PMID: 28091399
DOI: 10.4103/1008-682x.194420

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