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Article

Gene mutations in myeloproliferative neoplasms.

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2016

Araki Marito, Morishita Soji, Komatsu Norio

Abstract excerpt

This review outlines recent advances in the understanding of gene alterations and the genetic background associated with myeloproliferative neoplasms (MPNs), as well as describing the roles of these genetic factors in the development of MPNs. JAK2, CALR, and MPL mutations that are specifically found in patients with MPNs have been shown to constitutively activate cytokine receptors. Other mutations that are...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28090022
DOI: 10.11406/rinketsu.57.2526

Genes

CALR
JAK2
MPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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