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Article

Genetic analysis of chromosome 2 copy-neutral loss of heterozygosity in paternity testing.

International journal of legal medicine - 1 Mar 2026

Xu Guidan, Huang Yu, Liang Juhua, Huang Chunchuan, Nong Xuejuan, Lin Fengqiu, Chen Dingguo, Lu Zhenglin, Chang Zhengyi, Hu Rentong, Wang Chunfang

Abstract excerpt

This study investigates the cause of a non-Mendelian inheritance pattern observed at short tandem repeat (STR) loci on chromosome 2 in a paternity test and aims to provide a definitive identification opinion. STR genotyping was performed using the AGCU Expressmarker 22, Goldeneye DNA Identification System 22NC, and AGCU X Plus STR kits. Additionally, chromosomal microarray analysis (CMA) was used to assess copy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41160122
DOI: 10.1007/s00414-025-03638-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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