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Article

Impact on DNA Methylation in Cancer Prevention and Therapy by Bioactive Dietary Components

13 May 2010

Abstract excerpt

It is well established that aberrant gene regulation by epigenetic mechanisms can develop as a result of pathological processes such as cancer. Methylation of CpG islands is an important component of the epigenetic code and a number of genes become abnormally methylated during tumorigenesis. Some bioactive food components have been shown to have cancer inhibition activities by reducing DNA hypermethylation of key...

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PMID: 20423306
DOI: 10.2174/092986710791299966

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