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An Activating Mutation in STAT3 Results in Neonatal Diabetes Through Reduced Insulin Synthesis.

Diabetes - 1 Apr 2017

Velayos Teresa, Martínez Rosa, Alonso Milagros, Garcia-Etxebarria Koldo, Aguayo Anibal, Camarero Cristina, Urrutia Inés, Martínez de LaPiscina Idoia, Barrio Raquel, Santin Izortze, Castaño Luis

Abstract excerpt

Neonatal diabetes mellitus (NDM) is a rare form of diabetes diagnosed within the first 6 months of life. Genetic studies have allowed the identification of several genes linked to the development of NDM; however, genetic causes for ∼20% of the cases remain to be clarified. Most cases of NDM involve isolated diabetes, but sometimes NDM appears in association with other pathological conditions, including autoimmune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28073828
DOI: 10.2337/db16-0867

Genes

STAT3

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