Article
Association Study with 77 SNPs Confirms the Robust Role for the rs10830963/G of MTNR1B Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus Development.
PloS one - 1 Jan 2017
Rosta Klara, Al-Aissa Zahra, Hadarits Orsolya, Harreiter Jürgen, Nádasdi Ákos, Kelemen Fanni, Bancher-Todesca Dagmar, Komlósi Zsolt, Németh László, Rigó János, Sziller István, Somogyi Anikó, Kautzky-Willer Alexandra, Firneisz Gábor
Abstract excerpt
CONTEXT: Genetic variation in human maternal DNA contributes to the susceptibility for development of gestational diabetes mellitus (GDM). OBJECTIVE: We assessed 77 maternal single nucleotide gene polymorphisms (SNPs) for associations with GDM or plasma glucose levels at OGTT in pregnancy. METHODS: 960 pregnant women (after dropouts 820: case/control: m99'WHO: 303/517, IADPSG: 287/533) were enrolled in two...
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