Article
Microheterogeneity of orosomucoid in pathological conditions.
Electrophoresis - 1 Jan 2000
Hansen J E, Bøg-Hansen T C, Pedersen B, Neland K
Abstract excerpt
Studies of orosomucoid (alpha 1-acid glycoprotein) in human serum have revealed that orosomucoid is a mixture of molecules with differences in the glycan chains. This microheterogeneity has been studied using crossed affinoimmuno-electrophoresis with the lectin concanavalin A which binds to biantennary glycans. The relative proportions of the three orosomucoid subtypes are altered in various pathological...
Topics
- Concanavalin A
- Genetic Variation
- Humans
- Immunoelectrophoresis
- Inflammation
- Orosomucoid