Article
Activated ADI pathway: the initiator of intermediate vancomycin resistance in Staphylococcus aureus.
Canadian journal of microbiology - 1 Mar 2017
Tan Xin-Ee, Neoh Hui-Min, Looi Mee-Lee, Chin Siok Fong, Cui Longzhu, Hiramatsu Keiichi, Hussin Salasawati, Jamal Rahman
Abstract excerpt
Comparative proteomic profiling between 2 vancomycin-intermediate Staphylococcus aureus (VISA) strains, Mu50Ω-vraSm and Mu50Ω-vraSm-graRm, and vancomycin-susceptible S. aureus (VSSA) strain Mu50Ω revealed upregulated levels of catabolic ornithine carbamoyltransferase (ArcB) of the arginine catabolism pathway in VISA strains. Subsequent analyses showed that the VISA strains have higher levels of cellular ATP and...
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