Article
Case report: whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapies.
BMC cancer - 5 Jan 2017
Zhrebker Leah, Cherni Irene, Gross Lara M, Hinshelwood Margaret M, Reese Merrick, Aldrich Jessica, Guileyardo Joseph M, Roberts William C, Craig David, Von Hoff Daniel D, Mennel Robert G, Carpten John D
Abstract excerpt
BACKGROUND: Primary cardiac angiosarcomas are rare, but they are the most aggressive type of primary cardiac neoplasms. When patients do present, it is with advanced pulmonary and/or cardiac symptoms. Therefore, many times the correct diagnosis is not made at the time of initial presentation. These patients have metastatic disease and the vast majority of these patients die within a few months after diagnosis....
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