Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between Polymorphisms in Antioxidant Genes and Inflammatory Bowel Disease.

PloS one - 1 Jan 2017

Costa Pereira Cristiana, Durães Cecília, Coelho Rosa, Grácio Daniela, Silva Marco, Peixoto Armando, Lago Paula, Pereira Márcia, Catarino Telmo, Pinho Salomé, Teixeira João Paulo, Macedo Guilherme, Annese Vito, Magro Fernando

Abstract excerpt

Inflammation is the driving force in inflammatory bowel disease (IBD) and its link to oxidative stress and carcinogenesis has long been accepted. The antioxidant system of the intestinal mucosa in IBD is compromised resulting in increased oxidative injury. This defective antioxidant system may be the result of genetic variants in antioxidant genes, which can represent susceptibility factors for IBD, namely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to Glutathione Peroxidase

Share to Glutathione Peroxidase GPX1

Share to Inflammatory Bowel Diseases

Share to Polymorphism, Single Nucleotide

Share to Superoxide Dismutase

Source

Open in PubMed Open full text

Identifiers

PMID: 28052094
DOI: 10.1371/journal.pone.0169102
PMCID: PMC5215755

Genes

GPX1
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between Polymorphisms in Antioxidant Genes and Inflammatory Bowel Disease.PMID 28052094Read ↗

Evaluation of Effect CAT -262C/T, SOD + 35A/C, GPx1 Pro197Leu Polymorphisms in Patients with IBD in the Polish Population.Semantic proximity Read ↗

Antioxidants as Protection against Reactive Oxidative Stress in Inflammatory Bowel DiseaseSemantic proximity Read ↗

Inflammatory bowel disease (IBD) locus 12: is glutathione peroxidase-1 (GPX1) the relevant gene?Semantic proximity Read ↗

Evaluation of glutathione peroxidase and superoxide dismutase enzyme polymorphisms in celiac disease patients.Semantic proximity Read ↗

Relationships between single nucleotide polymorphisms of antioxidant enzymes and disease.Semantic proximity Read ↗

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel diseaseSemantic proximity Read ↗

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

Involvement of NAD(P)H:quinone oxidoreductase 1 and superoxide dismutase polymorphisms in ulcerative colitis.Semantic proximity Read ↗

The Role of Vitamin D and Vitamin D Receptor Gene Polymorphisms in the Course of Inflammatory Bowel Disease in Children.Semantic proximity Read ↗

Association of Glutathione S-Transferase M1 null genotype with inflammatory bowel diseases: A systematic review and meta-analysis.Semantic proximity Read ↗

Enzymatic Oxidants, Antioxidants, and Inflammatory Bowel DiseaseSemantic proximity Read ↗

Antioxidant-rich diet, GSTP1 rs1871042 polymorphism, and gastric cancer risk in a hospital-based case-control studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.