Article
Outcome of EGFR inhibitors treatment in advanced NSCLC patients, not enrolled in clinical trials.
Neoplasma - 1 Jan 2000
Mencoboni M, Filiberti R A, Taveggia P, Bruzzone A, Garuti A, Del Corso L, Ginocchio E, Brianti A, Simonassi C, Zucali P
Abstract excerpt
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have become a treatment after first-line chemotherapy in patients with advanced NSCLC. We assessed the predictive and prognostic role of EGFR and Kras mutations in NSCLC patients treated with TKIs after progression, not included in clinical trials. Gefitinib 250 mg or Erlotinib 150 mg per os were administered to 70 patients. Radiological...
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