Article
(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.
Trends in parasitology - 1 Apr 2017
Cosseau Céline, Wolkenhauer Olaf, Padalino Gilda, Geyer Kathrin K, Hoffmann Karl F, Grunau Christoph
Abstract excerpt
The G×E concept, in which genotype × environment interactions bring about the phenotype, is widely used to describe biological phenomena. We propose to extend the initial notion of the concept, replacing G by 'inheritance system'. This system, comprised of both genome and epigenome components, collectively interacts with the environment to shape the development of a phenotype. In the case of the human blood fluke...
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