Phenotypic characterization of circulating tumor cells in triple negative breast cancer patients.

doi:10.18632/oncotarget.14144

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Article

Phenotypic characterization of circulating tumor cells in triple negative breast cancer patients.

Oncotarget - 17 Jan 2017

Agelaki Sofia, Dragolia Melina, Markonanolaki Harris, Alkahtani Saad, Stournaras Christos, Georgoulias Vassilis, Kallergi Galatea

Abstract excerpt

INTRODUCTION: Patients with triple negative breast cancer (TNBC), are considered as a poor prognosis group for whom no targeted therapies are currently available. The aim of the present study was to phenotypically characterize their CTCs in order to explore potential therapeutic targets. METHODS: PBMC's cytospins were prepared from 45 early (before and after adjuvant chemotherapy), 10 metastatic TNBC and 21...

Topics

Adult
Aged
Aged, 80 and over
Cell Line, Tumor
Chemotherapy, Adjuvant
ErbB Receptors
Female
Humans
Keratins
MCF-7 Cells
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Metastasis

Neoplastic Cells, Circulating

Phenotype

Receptor, ErbB-2

Receptors, Estrogen

Receptors, Progesterone

Triple Negative Breast Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28029660
DOI: 10.18632/oncotarget.14144
PMCID: PMC5354910

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28029660-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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