Genetic Factors in Selected Complex Congenital Malformations with Cleft Defect.

doi:10.17219/acem/61911

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Article

Genetic Factors in Selected Complex Congenital Malformations with Cleft Defect.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2000

Wójcicki Piotr, Koźlik Maciej J, Wójcicka Karolina

Abstract excerpt

Cleft lips, alveolar ridges and palates are among the most common birth defects. There are over 500 different complex genetic disorders that include cleft defects. The most common related defects include abnormalities of the skeleton, skull, cardiovascular and nervous system. The occurrence of a cleft results from the interplay of multiple genes and environmental factors. Several thousand different mutations...

Topics

Abnormalities, Multiple
Cleft Lip
Genetic Predisposition to Disease
Humans

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Open in PubMed

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PMID: 28028964
DOI: 10.17219/acem/61911

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