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Article

Shared decision-making following disclosure of coronary heart disease genetic risk: results from a randomized clinical trial.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Mar 2017

Jouni Hayan, Haddad Raad A, Marroush Tariq S, Brown Sherry-Ann, Kruisselbrink Teresa M, Austin Erin E, Shameer Khader, Behnken Emma M, Chaudhry Rajeev, Montori Victor M, Kullo Iftikhar J

Abstract excerpt

Whether disclosure of genetic risk for coronary heart disease (CHD) influences shared decision-making (SDM) regarding use of statins to reduce CHD risk is unknown. We randomized 207 patients, age 45-65 years, at intermediate CHD risk, and not on statins, to receive the 10-year risk of CHD based on conventional risk factors alone (n=103) or in combination with a genetic risk score (n=104). A genetic counselor...

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Share to Coronary Disease
Share to Decision Making

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disclosure

Share to Genetic Predisposition to Disease

Share to Myocardial Infarction

Share to Patient Satisfaction

Share to Physicians

Share to Risk Factors

Source

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Identifiers

PMID: 27993947
DOI: 10.1136/jim-2016-000318
PMCID: PMC5325770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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