Article
The Immune Responses and Calcification of Bioprostheses in the α1,3-Galactosyltransferase Knockout Mouse.
The Journal of heart valve disease - 1 Mar 2016
Sung Jeong Woo, Jin Kim Yong, Lim Hong-Gook, Jung Saeromi, Ryul Lee Jeong
Abstract excerpt
BACKGROUND: The study aim was to evaluate the immune reaction, difference of degenerative calcification, and anti-calcification effect of decellularization with or without α-galactosidase in bovine pericardium and porcine heart valves, using an α1,3-galactosyltransferase (α-Gal) knockout (KO) mouse model. METHODS: In order to elucidate the anti-calcification effect of decellularization with or without...
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