Article
Thymic Function Impacts the Peripheral CD4/CD8 Ratio of HIV-Infected Subjects.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jan 2017
Rosado-Sánchez I, Herrero-Fernández I, Genebat M, Ruiz-Mateos E, Leal M, Pacheco Yolanda M
Abstract excerpt
BACKGROUND: The persistence of an inverted CD4/CD8 ratio has been extensively associated with the increased morbimortality of chronic human immunodeficiency virus (HIV)-infected subjects. Thymic function is crucial for the maintenance of T cell homeostasis. We explored the impact of thymic function on the CD4/CD8 ratio of HIV-infected subjects. METHODS: In a cohort of 53 antiretroviral-naive HIV-infected...
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