Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Case of Resistance to Thyroid Hormone (RTH) with a Negative Family History with Diagnosis Based on Persistent Palpitations.

Journal of UOEH - 1 Jan 2000

Kurozumi Akira, Okada Yosuke, Arao Tadashi, Tanaka Yoshiya

Abstract excerpt

Approximately 140 different mutations of thyroid hormone receptor β (TRβ) have been identified in resistance to thyroid hormone (RTH). We report herein a middle-aged man with a negative family history who was diagnosed with RTH based on persistent palpitations. Genetic analysis showed a TRβ mutation causing the substitution of alanine for proline 453 (P453A) in exon 10. Since treatment of RTH is different from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Base Sequence
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Thyroid Hormone Receptors beta

Share to Thyroid Hormone Resistance Syndrome

Share to Thyrotropin

Source

Identifiers

PMID: 27980311
DOI: 10.7888/juoeh.38.291

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Case of Resistance to Thyroid Hormone (RTH) with a Negative Family History with Diagnosis Based on Persistent Palpitations.PMID 27980311Read ↗

Thyroid hormone receptor beta gene mutation (P453A) in a family producing resistance to thyroid hormone.Semantic proximity Read ↗

A case of resistance to thyroid hormone beta and literature review: Case report.Semantic proximity Read ↗

Resistance to Thyroid Hormones: A Case-Series Study.Semantic proximity Read ↗

A new TRβ mutation in resistance to thyroid hormone syndrome.Semantic proximity Read ↗

A family of RTHβ with p.R316C mutation presenting occasional syndrome of inappropriate secretion of TSH.Semantic proximity Read ↗

Two Novel Mutations in the Thyroid Hormone Receptor β in Patients with Resistance to Thyroid Hormone (RTH β): Clinical, Biochemical, and Molecular Data.Semantic proximity Read ↗

Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor β Gene Mutation.Semantic proximity Read ↗

Clinical features and genetic analysis of four Brazilian kindreds with resistance to thyroid hormone.Semantic proximity Read ↗

Identification of four novel mutations in the thyroid hormone receptor-β gene in 164 Spanish and 2 Greek patients with resistance to thyroid hormone.Semantic proximity Read ↗

Three novel mutations of thyroid hormone receptor beta gene in unrelated patients with resistance to thyroid hormone: two mutations of the same codon (H435L and H435Q) produce separate subtypes of resistance.Semantic proximity Read ↗

A novel mutation (M310L) in the thyroid hormone receptor beta causing resistance to thyroid hormone in a Brazilian kindred and a neonate.Semantic proximity Read ↗

Clinical and genetic characteristics of a large monocentric series of patients affected by thyroid hormone (Th) resistance and suggestions for differential diagnosis in patients without mutation of Th receptor β.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.