Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon Cancer

15 Dec 2016

Abstract excerpt

Abstract Colorectal cancer causes 0.5 million deaths each year. To combat this type of cancer the development of new specific drug candidates is urgently needed. In the present work seven novel thymoquinone–artemisinin hybrids with different linkers were synthesized and tested for their in vitro anticancer activity against a panel of various tumor cell lines. The thymoquinone–artesunic acid hybrid 7 a, in which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioactive Compounds and Antitumor Agents
Share to Pharmacological Effects of Natural Compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27973725
DOI: 10.1002/cmdc.201600594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon CancerPMID 27973725Read ↗

Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer CellsSemantic proximity Read ↗

Thymoquinone Radiosensitizes Human Colorectal Cancer Cells in 2D and 3D Culture ModelsSemantic proximity Read ↗

Fluoroquinolones Hybrid Molecules as Promising Antibacterial Agents in the Fight against Antibacterial ResistanceSemantic proximity Read ↗

Coumarin‐containing hybrids and their antibacterial activitiesSemantic proximity Read ↗

Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeuticsSemantic proximity Read ↗

Effects of Thymoquinone–Fatty Acid Conjugates on Cancer CellsSemantic proximity Read ↗

New Hybrids Based on Curcumin and Resveratrol: Synthesis, Cytotoxicity and Antiproliferative Activity against Colorectal Cancer CellsSemantic proximity Read ↗

Synthesis, Antibacterial Activities, Mode of Action and Acute Toxicity Studies of New Oxazolidinone-Fluoroquinolone HybridsSemantic proximity Read ↗

Indole Alkaloids, Synthetic Dimers and Hybrids with Potential In Vivo Anticancer ActivitySemantic proximity Read ↗

Biotherapeutic potential and mechanisms of action of colchicineSemantic proximity Read ↗

A Glimpse at the Quinoline-Hybridization Approach for the Development of New AntimalarialsSemantic proximity Read ↗

Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.