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Zika Virus RNA Replication and Persistence in Brain and Placental Tissue

12 Dec 2016

Abstract excerpt

Zika virus is causally linked with congenital microcephaly and may be associated with pregnancy loss. However, the mechanisms of Zika virus intrauterine transmission and replication and its tropism and persistence in tissues are poorly understood. We tested tissues from 52 case-patients: 8 infants with microcephaly who died and 44 women suspected of being infected with Zika virus during pregnancy. By reverse...

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PMID: 27959260
DOI: 10.3201/eid2303.161499

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