Article
Close genetic relationships between a spousal pair with autism-affected children and high minor allele content in cases in autism-associated SNPs.
Genomics - 1 Jan 2017
Zhu Zuobin, Lu Xitong, Yuan Dejian, Huang Shi
Abstract excerpt
Parents of children affected with autism spectrum disorders (ASD) often have mild forms of autistic-like characteristics. Past studies have focused on searching for individual genetic risk loci of ASD. Here we studied the overall properties of the genomes of ASD trios by using previously published genome-wide data for common SNPs. The pairwise genetic distance (PGD) between a spousal pair with ASD-affected...
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