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Article

L-form transformation phenomenon in Mycobacterium tuberculosis associated with drug tolerance to ethambutol

8 Jul 2016

Abstract excerpt

OBJECTIVE/BACKGROUND: Cell wall-deficient bacterial forms (L-forms) may occur along with resistance to factors that trigger their appearance. It is of interest to study the relationship between the L-form transformation of Mycobacterium tuberculosis and the exhibition of drug tolerance to ethambutol (EMB), an inhibitor of cell wall synthesis. METHODS: L-form variant was produced from a sensitive EMB strain of M....

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Identifiers

PMID: 27931687
DOI: 10.1016/j.ijmyco.2016.06.011

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