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Evolution of mitosome metabolism and invasion-related proteins in Cryptosporidium

1 Dec 2016

Abstract excerpt

BACKGROUND: The switch from photosynthetic or predatory to parasitic life strategies by apicomplexans is accompanied with a reductive evolution of genomes and losses of metabolic capabilities. Cryptosporidium is an extreme example of reductive evolution among apicomplexans, with losses of both the mitosome genome and many metabolic pathways. Previous observations on reductive evolution were largely based on...

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PMID: 27931183
DOI: 10.1186/s12864-016-3343-5

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