Relevance of necroptosis in cancer

doi:10.1038/icb.2016.120

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Article

Relevance of necroptosis in cancer

6 Dec 2016

Abstract excerpt

Resistance to caspase-dependent apoptosis is often responsible for treatment failures in cancer. Finding novel therapeutic strategies that can activate alternative cell death programs appears to be appealing. Necroptosis is a form of programmed necrosis that occurs under caspase-deficient conditions. This alternative form of cell death has recently emerged as a potential anticancer therapy that could overcome...

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PMID: 27922620
DOI: 10.1038/icb.2016.120

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