Article
Human epidermal stem cells: Role in adverse skin reactions and carcinogenesis from radiation.
Mutation research. Reviews in mutation research - 1 Jan 2000
Martin Michèle T, Vulin Adeline, Hendry Jolyon H
Abstract excerpt
In human skin, keratinopoiesis is based on a functional hierarchy among keratinocytes, with rare slow-cycling stem cells responsible for the long-term maintenance of the tissue through their self-renewal potential, and more differentiated daughter progenitor cells actively cycling to permit epidermal renewal and turn-over every month. Skin is a radio-responsive tissue, developing all types of radiation damage and...
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