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Article

Dysregulation of mRNA Localization and Translation in Genetic Disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Nov 2016

Wang Eric T, Taliaferro J Matthew, Lee Ji-Ann, Sudhakaran Indulekha P, Rossoll Wilfried, Gross Christina, Moss Kathryn R, Bassell Gary J

Abstract excerpt

RNA-binding proteins (RBPs) acting at various steps in the post-transcriptional regulation of gene expression play crucial roles in neuronal development and synaptic plasticity. Genetic mutations affecting several RBPs and associated factors lead to diverse neurological symptoms, as characterized by neurodevelopmental and neuropsychiatric disorders, neuromuscular and neurodegenerative diseases, and can often be...

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Identifiers

PMID: 27911744
DOI: 10.1523/JNEUROSCI.2352-16.2016
PMCID: PMC5125209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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