Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular determinants of pathogenesis and clinical phenotype in myeloproliferative neoplasms.

Haematologica - 1 Jan 2017

Grinfeld Jacob, Nangalia Jyoti, Green Anthony R

Abstract excerpt

The myeloproliferative neoplasms are a heterogeneous group of clonal disorders characterized by the overproduction of mature cells in the peripheral blood, together with an increased risk of thrombosis and progression to acute myeloid leukemia. The majority of patients with Philadelphia-chromosome negative myeloproliferative neoplasms harbor somatic mutations in Janus kinase 2, leading to constitutive activation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Disease Susceptibility
Share to Environment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Myeloproliferative Disorders

Share to Phenotype

Share to Receptors, Cytokine

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 27909216
DOI: 10.3324/haematol.2014.113845
PMCID: PMC5210228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular determinants of pathogenesis and clinical phenotype in myeloproliferative neoplasms.PMID 27909216Read ↗

Myeloproliferative Neoplasms.Semantic proximity Read ↗

Genetics of Myeloproliferative Neoplasms.Semantic proximity Read ↗

New insights into the pathogenesis and treatment of chronic myeloproliferative disorders.Semantic proximity Read ↗

Pathogenesis of Myeloproliferative DisordersSemantic proximity Read ↗

Biology and therapeutic targeting of molecular mechanisms in MPNs.Semantic proximity Read ↗

Myeloproliferative Neoplasms: A Contemporary Review.Semantic proximity Read ↗

From Janus kinase 2 to calreticulin: the clinically relevant genomic landscape of myeloproliferative neoplasms.Semantic proximity Read ↗

World Health Organization Classification, Evaluation, and Genetics of the Myeloproliferative Neoplasm VariantsSemantic proximity Read ↗

Clinical and molecular genetic characterization of myelofibrosis.Semantic proximity Read ↗

Myeloproliferative neoplasms: from origins to outcomes.Semantic proximity Read ↗

Myeloproliferative neoplasms: from origins to outcomes.Semantic proximity Read ↗

[CURRENT CRITERIA FOR THE DIAGNOSIS OF MYELOPROLIFERATIVE NEOPLASMS - WHAT IS IMPORTANT TO KNOW?]Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.