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Article

Preimplantation factor is an anti-apoptotic effector in human trophoblasts involving p53 signaling pathway

1 Dec 2016

Abstract excerpt

From the earliest stages of gestation, embryonic-maternal interaction has a key role in a successful pregnancy. Various factors present during gestation may significantly influence this type of juxta/paracrine interaction. PreImplantation Factor (PIF) is a recently identified factor with activity at the fetomaternal interface. PIF is secreted by viable embryos and directly controls placental development by...

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PMID: 27906186
DOI: 10.1038/cddis.2016.382

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