Article
Characterization of the Pathogenicity of Streptococcus intermedius TYG1620 Isolated from a Human Brain Abscess Based on the Complete Genome Sequence with Transcriptome Analysis and Transposon Mutagenesis in a Murine Subcutaneous Abscess Model.
Infection and immunity - 1 Feb 2017
Hasegawa Noriko, Sekizuka Tsuyoshi, Sugi Yutaka, Kawakami Nobuhiro, Ogasawara Yumiko, Kato Kengo, Yamashita Akifumi, Takeuchi Fumihiko, Kuroda Makoto
Abstract excerpt
Streptococcus intermedius is known to cause periodontitis and pyogenic infections in the brain and liver. Here we report the complete genome sequence of strain TYG1620 (genome size, 2,006,877 bp; GC content, 37.6%; 2,020 predicted open reading frames [ORFs]) isolated from a brain abscess in an infant. Comparative analysis of S. intermedius genome sequences suggested that TYG1620 carries a notable type VII...
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