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Accelerated Placental Aging in Early Onset Preeclampsia Pregnancies Identified By DNA Methylation

29 Nov 2016

Abstract excerpt

AIM: To determine whether dynamic DNA methylation changes in the human placenta can be used to predict gestational age. MATERIALS & METHODS: Publicly available placental DNA methylation data from 12 studies, together with our own dataset, using Illumina Infinium Human Methylation BeadChip arrays. RESULTS & CONCLUSION: We developed an accurate tool for predicting gestational age of placentas using 62 CpG sites....

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PMID: 27894195
DOI: 10.2217/epi-2016-0103

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