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Article

Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells.

Scientific reports - 28 Nov 2016

Zakrzewicz Dariusz, Bergmann Simone, Didiasova Miroslava, Giaimo Benedetto Daniele, Borggrefe Tilman, Mieth Maren, Hocke Andreas C, Lochnit Guenter, Schaefer Liliana, Hammerschmidt Sven, Preissner Klaus T, Wygrecka Malgorzata

Abstract excerpt

Streptococcus pneumoniae is the most frequent cause of community-acquired pneumonia. The infection process involves bacterial cell surface receptors, which interact with host extracellular matrix components to facilitate colonization and dissemination of bacteria. Here, we investigated the role of host-derived extracellular RNA (eRNA) in the process of pneumococcal alveolar epithelial cell infection. Our study...

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Identifiers

PMID: 27892961
DOI: 10.1038/srep37758
PMCID: PMC5125276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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